Vitamin C

VITAMIN C (ascorbic acid) is not available in our injections. Ascorbic acid is generally well tolerated + absorbed when taken orally. It can’t be mixed with all B vitamins in solution for injection + can be very painful as an intramuscular (IM) shot. Typically, the most that can be tolerated in an IM shot is about 150-250 mg, whereas when taken orally most people can tolerate 3,000-6,000 mg (3-6 grams) before it causes loose stools.

Overloading the body with supplemental vitamin C may result in the formation of calcifications + kidney stones in the urinary tract. Vitamin C is metabolized to oxalate + excreted in urine potentially increasing the risk for calcium oxalate stone formation, especially in men (Curhan et al., 1999; Auer et al., 2001; Thomas et al., 2013; Ferraro et al., 2016).

Vitamin D

VITAMIN D is not available in our injections. Vitamin D is a lipid (fat) soluble vitamin + stores in the body making it potentially toxic. One should not supplement with vitamin D unless a recent blood panel has been evaluated + supplementation with proper dosing has been prescribed by a qualified healthcare provider after reviewing recent labs. Supplementing with vitamin D can cause health issues in persons with certain conditions including artherosclerosis (hardening of the arteries), histoplasmosis, hyperparathyroidism, lymphoma, kidney disease, sarcoidosis + tuberculosis. Supplementation with D in those with elevated serum calcium levels may make the condition worse + put the individual at risk for kidney stones. Supplementation with D in those with vitamin K deficiency may induce long-term soft tissue calcification + cardiovascular disease.

Folate/Folic Acid

FOLATE/FOLIC ACID is not available in our injections. It can cause serious issues in those with MTHFR + people with pernicious anemia.

Approximately 60% of the population has a genetic defect of the MTHFR gene, which can cause an issue with methylation in the body. Those who can’t efficiently convert folic acid into its methylated form for proper absorption tend to have high serum levels of folic acid, low serotonin, high histamine + are considered to be under-methylated. Administering folic acid to an under-methylated individual can not only make them feel much worse, it may increase their risk for developing cancer.

Some symptoms + traits of under-methylation include: chronic depression, history of perfectionism, seasonal allergies, high libido, addictiveness, phobias, obsessive compulsive tendencies, calm demeanor but high inner tension + frequent headaches.

Folic acid should not be administered to people with undiagnosed anemia. The most common sign of anemia is fatigue + because most people seeking a B12 shot have fatigue, it is highly likely some have undiagnosed anemia. Administration of folic acid to those with undiagnosed pernicious anemia may result in severe nervous system damage. Vitamin preparations containing folic acid should be avoided by those with pernicious anemia because folic acid may potentiate neurologic complications of vitamin B12 deficiency.


IRON is not available in our injections. It is highly toxic + should not be supplemented without the recommendation of a doctor who has evaluated recent blood work. It’s important to have a highly-skilled, trained professional who’s adept at Z-track injections administer an iron shot in a reclined position to reduce the risk of permanent skin discoloration (tattooing). Iron injections should only be done in a facility equipped for emergency care as they can cause severe or life-threatening reactions that can come on quickly.


References Cited

Auer, B.L., D. Auer, and A.L. Rodgers. 2001. Relative hyperoxaluria, crystalluria and haematuria after megadose ingestion of vitamin C. Eur J Clin Invest. 28(9):695-700. doi:10.1046/j.1365-2362.1998.00349.x

Curhan, G.C., W.C. Willett, F.E. Speizer, and M.J. Stampfer. 1999. Intake of vitamins B6 and C and the risk of kidney stones in women. J Am Soc Nephrol. 10(4):840-845. [link]

Ferraro, P.M., G.C. Curhan, G. Gambaro, and E.N. Taylor. 2016. Total, dietary, and supplemental vitamin C intake and risk of incident kidney stones. AJKD. 67(3):400-407. doi:10.1053/j.ajkd.2015.09.005

Thomas, L.D.K., C.G. Elinder, H.G. Tiselius, et al. 2013. Ascorbic acid supplements and kidney stone incidence among men: a prospective study. JAMA Intern Med. 173(5):386–388. doi:10.1001/jamainternmed.2013.2296